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Dedifferentiated liposarcoma

3 associated genes
No signs/symptoms info

PROTEIN INTERACTIONS: 1

Hypoparathyroidism - deafness - renal disease

1 OMIM reference -
1 associated gene
21 signs/symptoms

Dedifferentiated liposarcoma

Hypoparathyroidism - deafness - renal disease

CDK4	(UniProt - OMIM)		GATA3	(UniProt - OMIM)
HMGA2	(UniProt - OMIM)
MDM2	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	MDM2	(0.63)	GATA3

Citations in the biomedical literature:

Dedifferentiated liposarcoma		Hypoparathyroidism - deafness - renal disease
	Synonym(s): - DDLS		Synonym(s): - Barakat syndrome - HDR syndrome

	Classification (Orphanet): - Rare oncologic disease		Classification (Orphanet): - Rare developmental defect during embryogenesis - Rare endocrine disease - Rare genetic disease - Rare otorhinolaryngologic disease - Rare renal disease

	Classification (ICD10): - Neoplasms -		Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -

	Epidemiological data: Class of prevalence: unknown Average age onset: adulthood Average age of death: adult Type of inheritance: sporadic		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: childhood Average age of death: - Type of inheritance: autosomal dominant

	External references: No OMIM references No MeSH references		External references: 1 OMIM reference - No MeSH references

Hypoparathyroidism - deafness - renal disease
	Very frequent - Autosomal dominant inheritance - Hypocalcemia - Hypoparathyroidy - Sensorineural deafness / hearing loss Frequent - Agenesis / hypoplasia / aplasia of kidneys - Contractures / cramps / trismus / tetania / claudication / opisthotonos - Humour troubles / anxiety / depression / apathy / euphoria / irritability - Seizures / epilepsy / absences / spasms / status epilepticus Occasional - Ectopic / horseshoe / fused kidneys - Failure to thrive / difficulties for feeding in infancy / growth delay - Gastric / pyloric stenosis - Hematuria / microhematuria - Multicystic kidney / renal dysplasia - Nystagmus - Proteinuria - Psoriasis - Ptosis - Renal failure - Retinitis pigmentosa / retinal pigmentary changes - Ventricular septal defect / interventricular communication - Vesicorenal / vesicoureteral reflux
Dedifferentiated liposarcoma
(no data available)